PDB entry 4g48

View 4g48 on RCSB PDB site
Description: Structure of CYP121 in complex with 4-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-diol
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: P450, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2012-07-16, released 2012-09-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-09-19, with a file datestamp of 2012-09-14.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.171
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 121
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: Rv2276
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4g48a_
  • Heterogens: HEM, SO4, PZB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4g48A (A:)
mtatvllevpfsargdripdavaelrtrepirkvrtitgaeawlvssyalctqvledrrf
smketaaagaprlnaltvppevvnnmgniadaglrkavmkaitpkapgleqflrdtansl
ldnlitegapadlrndfadplatalhckvlgipqedgpklfrslsiafmssadpipaaki
nwdrdieymagilenpnittglmgelsrlrkdpayshvsdelfatigvtffgagvistgs
flttalisliqrpqlrnllhekpelipagveellrinlsfadglprlatadiqvgdvlvr
kgelvlvlleganfdpehfpnpgsieldrpnptshlafgrgqhfcpgsalgrrhaqigie
allkkmpgvdlavpidqlvwrtrfqrriperlpvlw

    Sequence, based on observed residues (ATOM records): (download) 
    >4g48A (A:)
tatvllevpfsargdripdavaelrtrepirkvrtitgaeawlvssyalctqvledrrfs
mketaaagaprlnaltvppevvnnmgniadaglrkavmkaitpkapgleqflrdtansll
dnlitegapadlrndfadplatalhckvlgipqedgpklfrslsiafmssadpipaakin
wdrdieymagilenpnittglmgelsrlrkdpayshvsdelfatigvtffgagvistgsf
lttalisliqrpqlrnllhekpelipagveellrinlsfadglprlatadiqvgdvlvrk
gelvlvlleganfdpehfpnpgsieldrpnptshlafgrgqhfcpgsalgrrhaqigiea
llkkmpgvdlavpidqlvwrtrfqrriperlpvlw