PDB entry 4fv8

View 4fv8 on RCSB PDB site
Description: Crystal Structure of the ERK2 complexed with E63
Class: transferase
Keywords: transferase
Deposited on 2012-06-29, released 2012-08-29
The last revision prior to the SCOPe 2.02 freeze date was dated 2012-08-29, with a file datestamp of 2012-08-24.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.188
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ERK2, MAPK1, PRKM1, PRKM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4fv8a_
  • Heterogens: E63, SO4, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4fv8A (A:)
maaaaaagagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfe
hqtycqrtlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqh
lsndhicyflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdh
tgflteyvatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhi
lgilgspsqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphk
rieveqalahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgyrs

    Sequence, based on observed residues (ATOM records): (download) 
    >4fv8A (A:)
gagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqr
tlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhic
yflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvavatrwyrapeiml
nytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarny
llslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydpsdep
iaeapfkfdmelddlpkeklkelifeetarfqpg