PDB entry 4fsa

View 4fsa on RCSB PDB site
Description: tRNA-Guanine Transglycosylase soaked with pyridyl-alkine-substituted lin-benzoguanine ligand
Class: TRANSFERASE/TRANSFERASE inhibitor
Keywords: TIM BARREL, GLYCOSYLTRANSFERASE, QUEUOSINE, BIOSYNTHESIS, TRANSFERASE, TRNA PROCESSING, TRNA, TRANSFERASE-TRANSFERASE inhibitor complex
Deposited on 2012-06-27, released 2013-07-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • cloning artifact (311)
    Domains in SCOPe 2.08: d4fsaa_
  • Heterogens: ZN, 0V3, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4fsaA (A:)
    mveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvr
    atgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqsee
    gvtfkshldgsrhmlspersieiqhllgsdivmafdectpypatpsraassmersmrwak
    rsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqdem
    frvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpi
    nirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqk
    irdsisegrfsqfaqdfraryfarns
    

    Sequence, based on observed residues (ATOM records): (download)
    >4fsaA (A:)
    rprfsfsiaaregkartgtiemkrgvirtpafmpvgatvkalkpetvratgadiilgnty
    hlmlrpgaeriaklgglhsfmgwdrpiltdsgyqseegvtlspersieiqhllgsdivma
    fdetpypatpsraassmersmrwakrsrdafdsrkeqaenaalfgiqqgsvfenlrqqsa
    dalaeigfdgyavgglavgegqdemfrvldfsvpmlpddkphylmgvgkpddivgaverg
    idmfdcvlptrsgrngqaftwdgpinirnarfsedlkpldsechcavcqkwsrayihhli
    rageilgamlmtehniafyqqlmqkirdsisegrfsqfaqdfraryf