PDB entry 4frv

View 4frv on RCSB PDB site
Description: Crystal structure of mutated cyclophilin B that causes hyperelastosis cutis in the American Quarter Horse
Class: isomerase
Keywords: cyclophilin-type PPIase, Peptidyl-prolyl cis-trans isomerase; chaperone; foldase, P3H1-CRTAP-CypB complex; LH1 binding, endoplasmic reticulum, ISOMERASE
Deposited on 2012-06-26, released 2012-11-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.1 Å
R-factor: N/A
AEROSPACI score: 0.73 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: peptidyl-prolyl cis-trans isomerase
    Species: Equus caballus [TaxId:9796]
    Gene: PPIB
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5YBL8 (2-184)
      • expression tag (0-1)
      • see remark 999 (7)
    Domains in SCOPe 2.08: d4frva1, d4frva2
  • Heterogens: ZN, ME2, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4frvA (A:)
    amdekkkrpkvtvkvyfdlrigdedigrvviglfgktvpktvdnfvalatgekgfgykds
    kfhrvikdfmiqggdftrgdgtggksiygerfpdenfklkhygpgwvsmanagkdtngsq
    ffittvktawldgkhvvfgkvlegmevvrkvettktdgrdkplkdvtiadcgkievekpf
    aiake