PDB entry 4fr6

View 4fr6 on RCSB PDB site
Description: tRNA-Guanine Transglycosylase cocrystallized with pyridyl-alkine-substituted lin-benzoguanine ligand
Class: TRANSFERASE/TRANSFERASE inhibitor
Keywords: TIM BARREL, GLYCOSYLTRANSFERASE, QUEUOSINE, BIOSYNTHESIS, TRANSFERASE, TRNA PROCESSING, TRNA, TRANSFERASE-TRANSFERASE inhibitor complex
Deposited on 2012-06-26, released 2013-07-24
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-24, with a file datestamp of 2013-07-19.
Experiment type: XRAY
Resolution: 1.59 Å
R-factor: 0.164
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • cloning artifact (311)
    Domains in SCOPe 2.06: d4fr6a_
  • Heterogens: ZN, 0V3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4fr6A (A:)
mveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvr
atgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqsee
gvtfkshldgsrhmlspersieiqhllgsdivmafdectpypatpsraassmersmrwak
rsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqdem
frvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpi
nirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqk
irdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >4fr6A (A:)
rprfsfsiaaregkartgtiemkrgvirtpafmpvgtadiilgntyhlmlrpgaeriakl
gglhsfmgwdrpiltdsggyqvmslsqseegvtflspersieiqhllgsdivmafdectp
ypatpsraassmersmrwakrsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalae
igfdgyavgglavgegqdemfrvldfsvpmlpddkphylmgvgkpddivgavergidmfd
cvlptrsgrngqaftwdgpinirnarfsedlkpldsechcavcqkwsrayihhliragei
lgamlmtehniafyqqlmqkirdsisegrfsqfaqdfraryf