PDB entry 4fgg

View 4fgg on RCSB PDB site
Description: S. aureus dihydrofolate reductase co-crystallized with propyl-DAP isobutenyl-dihydrophthalazine inhibitor
Class: oxidoreductase/inhibitor
Keywords: dihydrofolate reductase, OXIDOREDUCTASE-INHIBITOR complex
Deposited on 2012-06-04, released 2013-01-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-11-20, with a file datestamp of 2013-11-15.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.202
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: dihydrofolate reductase
  Species: Staphylococcus aureus [TaxId:1280]
  Gene: DHFR, folA
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0A017 (0-158)
    • expression tag (159-162)
  Domains in SCOPe 2.08: d4fgga1, d4fgga2
• Heterogens: 0U5, NAP, GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4fggA (A:)
  mtlsilvahdlqrvigfenqlpwhlpndlkhvkklstghtlvmgrktfesigkplpnrrn
  vvltsdtsfnvegvdvihsiediyqlpghvfifggqtlfeemidkvddmyitviegkfrg
  dtffppytfedwevassvegkldekntiphtflhlirkklvpr