PDB entry 4fbx

View 4fbx on RCSB PDB site
Description: Complex structure of human protein kinase CK2 catalytic subunit crystallized in the presence of a bisubstrate inhibitor
Class: transferase/transferase inhibitor
Keywords: protein kinase fold, protein phosphorylation, Bisubstrate inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-05-23, released 2012-10-17
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-10-31, with a file datestamp of 2012-10-26.
Experiment type: XRAY
Resolution: 2.33 Å
R-factor: 0.202
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2A1, CK2A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4fbxa_
  • Chain 'B':
    Compound: bisubstrate inhibitor
    Database cross-references and differences (RAF-indexed):
    • PDB 4FBX (0-End)
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4fbxA (A:)
msgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainit
nnekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntd
fkqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglae
fyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnyd
qlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdf
ldkllrydhqsrltareamehpyfytvvkdqarmg

    Sequence, based on observed residues (ATOM records): (download) 
    >4fbxA (A:)
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqarm

  • Chain 'B':
    No sequence available.