PDB entry 4f9o

View 4f9o on RCSB PDB site
Description: Crystal Structure of recombinant human Hexokinase type I with 2-deoxy-Glucose 6-Phosphate
Class: transferase
Keywords: hexokinase, 2-deoxy Glucose-6-Phosphate, TRANSFERASE
Deposited on 2012-05-19, released 2013-06-12
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-06-12, with a file datestamp of 2013-06-07.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.241
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hexokinase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: HK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4f9oa1, d4f9oa2, d4f9oa3, d4f9oa4
  • Chain 'B':
    Compound: Hexokinase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: HK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4f9ob1, d4f9ob2, d4f9ob3, d4f9ob4
  • Heterogens: BGC, 0NZ, NA, CIT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4f9oA (A:)
miaaqllayyftelkddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptat
vkmlptfvrsipdgsekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivh
gsgsqlfdhvaeclgdfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgv
egadvvkllnkaikkrgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacyme
elrhidlvegdegrmcintewgafgddgsledirtefdreidrgslnpgkqlfekmvsgm
ylgelvrlilvkmakegllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlg
vepsdddcvsvqhvctivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykth
pqysrrfhktlrrlvpdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhlt
kdmllevkkrmraemelglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrv
llvkirsgkkrtvemhnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgf
tfsfpcqqtsldagilitwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvg
tmmtcayeeptcevglivgtgsnacymeemknvemvegdqgqmcinmewgafgdngcldd
irthydrlvdeyslnagkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrg
ifetkflsqiesdrlallqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaa
vvdkirenrgldrlnvtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkg
aalitavgvrlrte

    Sequence, based on observed residues (ATOM records): (download) 
    >4f9oA (A:)
ddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptatvkmlptfvrsipdgs
ekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivhgsgsqlfdhvaeclg
dfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgvegadvvkllnkaikk
rgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacymeelrhidlvegdegrm
cintewgafgddgsledirtefdreidrgslnpgkqlfekmvsgmylgelvrlilvkmak
egllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlgvepsdddcvsvqhvc
tivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykthpqysrrfhktlrrlv
pdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhltkdmllevkkrmraem
elglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrvllvkirsgkkrtvem
hnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgftfsfpcqqtsldagi
litwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvgtmmtcayeeptcevg
livgtgsnacymeemknvemvegdqgqmcinmewgafgdngclddirthydrlvdeysln
agkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrgifetkflsqiesdrl
allqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaavvdkirenrgldrln
vtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkgaalitavgvrlrte

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4f9oB (B:)
miaaqllayyftelkddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptat
vkmlptfvrsipdgsekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivh
gsgsqlfdhvaeclgdfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgv
egadvvkllnkaikkrgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacyme
elrhidlvegdegrmcintewgafgddgsledirtefdreidrgslnpgkqlfekmvsgm
ylgelvrlilvkmakegllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlg
vepsdddcvsvqhvctivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykth
pqysrrfhktlrrlvpdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhlt
kdmllevkkrmraemelglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrv
llvkirsgkkrtvemhnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgf
tfsfpcqqtsldagilitwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvg
tmmtcayeeptcevglivgtgsnacymeemknvemvegdqgqmcinmewgafgdngcldd
irthydrlvdeyslnagkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrg
ifetkflsqiesdrlallqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaa
vvdkirenrgldrlnvtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkg
aalitavgvrlrte

    Sequence, based on observed residues (ATOM records): (download) 
    >4f9oB (B:)
ddqvkkidkylyamrlsdetlidimtrfrkemknglsrdfnptatvkmlptfvrsipdgs
ekgdfialdlggssfrilrvqvnheknqnvhmesevydtpenivhgsgsqlfdhvaeclg
dfmekrkikdkklpvgftfsfpcqqskideailitwtkrfkasgvegadvvkllnkaikk
rgdydanivavvndtvgtmmtcgyddqhcevgliigtgtnacymeelrhidlvegdegrm
cintewgafgddgsledirtefdreidrgslnpgkqlfekmvsgmylgelvrlilvkmak
egllfegritpelltrgkfntsdvsaieknkeglhnakeiltrlgvepsdddcvsvqhvc
tivsfrsanlvaatlgailnrlrdnkgtprlrttvgvdgslykthpqysrrfhktlrrlv
pdsdvrfllsesgsgkgaamvtavayrlaeqhrqieetlahfhltkdmllevkkrmraem
elglrkqthnnavvkmlpsfvrrtpdgtengdflaldlggtnfrvllvkirsgkkrtvem
hnkiyaipieimqgtgeelfdhivscisdfldymgikgprmplgftfsfpcqqtsldagi
litwtkgfkatdcvghdvvtllrdaikrreefdldvvavvndtvgtmmtcayeeptcevg
livgtgsnacymeemknvemvegdqgqmcinmewgafgdngclddirthydrlvdeysln
agkqryekmisgmylgeivrnilidftkkgflfrgqisetlktrgifetkflsqiesdrl
allqvrailqqlglnstcddsilvktvcgvvsrraaqlcgagmaavvdkirenrgldrln
vtvgvdgtlyklhphfsrimhqtvkelspkcnvsfllsedgsgkgaalitavgvrlrte