PDB entry 4f1o

View 4f1o on RCSB PDB site
Description: Crystal Structure of the L1180T mutant Roco4 Kinase Domain from D. discoideum bound to AppCp
Class: Transferase, Signaling Protein
Keywords: Protein Kinase, LRRK2, ROCO, Kinase, ATP-binding, Nucleotide-binding, Serine/threonine-protein kinase, Transferase, Signaling Protein
Deposited on 2012-05-07, released 2012-06-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-07-11, with a file datestamp of 2012-07-06.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.252
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase roco4
    Species: Dictyostelium discoideum [TaxId:44689]
    Gene: DDB_G0288251, roco4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6XHB2 (13-286)
      • expression tag (11-12)
    Domains in SCOPe 2.07: d4f1oa1, d4f1oa2
  • Heterogens: ACP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4f1oA (A:)
gamggsefpksrlptladneieyekqigkggfglvhkgrlvkdksvvaikslilgdsege
temiekfqefqrevfimsnlnhpnivklyglmhnpprmvmefvpcgdlyhrlldkahpik
wsvklrlmldialgieymqnqnppivhrdlrspniflqsldenapvcakvadfgtsqqsv
hsvsgllgnfqwmapetigaeeesytekadtysfamilytiltgegpfdeysygkikfin
mireeglrptipedcpprlrnvielcwsgdpkkrphfsyivkelsel

    Sequence, based on observed residues (ATOM records): (download) 
    >4f1oA (A:)
rlptladneieyekqigkggfglvhkgrlvkdksvvaikslilgdsegetemiekfqefq
revfimsnlnhpnivklyglmhnpprmvmefvpcgdlyhrlldkahpikwsvklrlmldi
algieymqnqnppivhrdlrspniflqsldenapvcakvadfgtsqqsvhsvsgllgnfq
wmapetigaeeesytekadtysfamilytiltgegpfdeysygkikfinmireeglrpti
pedcpprlrnvielcwsgdpkkrphfsyivkelsel