PDB entry 4ez7

View 4ez7 on RCSB PDB site
Description: CDK2 in complex with staurosporine and 2 molecules of 8-anilino-1-naphthalene sulfonic acid
Class: transferase/antibiotic
Keywords: protein kinase, ANS, TRANSFERASE-ANTIBIOTIC complex
Deposited on 2012-05-02, released 2012-08-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-10-03, with a file datestamp of 2012-09-28.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: 0.22
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24941 (8-305)
      • expression tag (4-7)
    Domains in SCOPe 2.08: d4ez7a1, d4ez7a2
  • Heterogens: STU, 2AN, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ez7A (A:)
gplgspefmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstairei
sllkelnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqll
qglafchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrape
illgckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvts
mpdykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkp
vphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >4ez7A (A:)
spefmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllk
elnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqgla
fchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillg
ckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdy
kpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
rl