PDB entry 4eyr

View 4eyr on RCSB PDB site
Description: Crystal structure of multidrug-resistant clinical isolate 769 HIV-1 protease in complex with ritonavir
Class: hydrolase/hydrolase inhibitor
Keywords: Protease, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2012-05-01, released 2013-01-30
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-02-27, with a file datestamp of 2013-02-22.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.193
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: hiv-1 protease
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Gene: pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q000H7 (0-98)
    • varaint (24)
    • variant (34-35)
    • variant (45)
    • variant (24)
  Domains in SCOPe 2.05: d4eyra_
• Chain 'B':
  Compound: hiv-1 protease
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Gene: pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q000H7 (0-98)
    • varaint (24)
    • variant (34-35)
    • variant (45)
    • variant (24)
  Domains in SCOPe 2.05: d4eyrb_
• Heterogens: RIT, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4eyrA (A:)
  pqitlwqrpivtikiggqlkeallntgaddtvleevnlpgrwkpkliggiggfvkvrqyd
  qvpieicghkvigtvlvgptptnvigrnlmtqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4eyrB (B:)
  pqitlwqrpivtikiggqlkeallntgaddtvleevnlpgrwkpkliggiggfvkvrqyd
  qvpieicghkvigtvlvgptptnvigrnlmtqigctlnf