PDB entry 4ewl

View 4ewl on RCSB PDB site
Description: Crystal Structure of MshB with glycerol and Acetate bound in the active site
Class: hydrolase
Keywords: active site, glycerol, acetate, tyrosine 142, histidine 144, MshB, HYDROLASE
Deposited on 2012-04-27, released 2012-09-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-11-21, with a file datestamp of 2012-11-16.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.191
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: mshB, MT1207, Rv1170
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ewla_
  • Chain 'B':
    Compound: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: mshB, MT1207, Rv1170
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ewlb_
  • Heterogens: PE4, GOL, ZN, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4ewlA (A:)
msetprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadh
adqlggyrigeltaalralgvsapiylggagrwrdsgmagtdqrsqrrfvdadprqtvga
lvaiirelrphvvvtydpnggyghpdhvhthtvttaavaaagvgsgtadhpgdpwtvpkf
ywtvlglsalisgaralvpddlrpewvlpradeiafgysddgidavveadeqaraakvaa
laahatqvvvgptgraaalsnnlalpiladehyvlaggsagardergwetdllaglgft

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ewlB (B:)
msetprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadh
adqlggyrigeltaalralgvsapiylggagrwrdsgmagtdqrsqrrfvdadprqtvga
lvaiirelrphvvvtydpnggyghpdhvhthtvttaavaaagvgsgtadhpgdpwtvpkf
ywtvlglsalisgaralvpddlrpewvlpradeiafgysddgidavveadeqaraakvaa
laahatqvvvgptgraaalsnnlalpiladehyvlaggsagardergwetdllaglgft

    Sequence, based on observed residues (ATOM records): (download) 
    >4ewlB (B:)
msetprllfvhahpddeslsngatiahytsrgaqvhvvtctlgeegevigdrwaqltadh
adqlggyrigeltaalralgvsapiylggagrwrdsgmagtdqrsqrrfvdadprqtvga
lvaiirelrphvvvtydpnggyghpdhvhthtvttaavaaagvgdpwtvpkfywtvlgls
alisgaralvpddlrpewvlpradeiafgysddgidavveadeqaraakvaalaahatqv
vvgptgraaalsnnlalpiladehyvlaggsagardergwetdllaglgf