PDB entry 4esh

View 4esh on RCSB PDB site
Description: The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with deoxythymidine.
Class: transferase
Keywords: thymidylate kinase, structural genomics, PSI-Biology, protein structure initiative, midwest center for structural genomics, MCSG, structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI), TRANSFERASE
Deposited on 2012-04-23, released 2012-05-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-05-23, with a file datestamp of 2012-05-18.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.184
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Gene: PA2962, Pseudomonas aeruginosa, tmk
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HZN8 (3-End)
      • expression tag (1-2)
    Domains in SCOPe 2.06: d4esha1, d4esha2
  • Heterogens: THM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4eshA (A:)
snamtglfvtlegpegagkstnrdylaerlrergievqltrepggtplaerirelllaps
depmaadtelllmfaaraqhlagvirpalargavvlcdrftdatyayqgggrglpearia
alesfvqgdlrpdltlvfdlpveiglaraaargrldrfeqedrrffeavrqtylqraaqa
peryqvldaglplaevqagldrllpnllerlng

    Sequence, based on observed residues (ATOM records): (download) 
    >4eshA (A:)
namtglfvtlegpegagkstnrdylaerlrergievqltrepggtplaerirelllapsd
epmaadtelllmfaaraqhlagvirpalargavvlcdrftdatyayqgggrglpeariaa
lesfvqgdlrpdltlvfdlpveiglargrldrfeqedrrffeavrqtylqraaqaperyq
vldaglplaevqagldrllpnllerln