PDB entry 4en3

View 4en3 on RCSB PDB site
Description: Crystal structure of a human Valpha24(-) NKT TCR in complex with CD1d/alpha-galactosylceramide
Class: immune system
Keywords: Immunoglobulin-like, MHC class I-like, Antigen presentation-recognition, Membrane, IMMUNE SYSTEM
Deposited on 2012-04-12, released 2012-10-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.57 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: human nkt tcr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4EN3
    Domains in SCOPe 2.07: d4en3a1, d4en3a2, d4en3a3
  • Chain 'B':
    Compound: human nkt tcr beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • PDB 4EN3
    Domains in SCOPe 2.07: d4en3b1, d4en3b2
  • Chain 'C':
    Compound: Antigen-presenting glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4en3c1, d4en3c2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4en3d_
  • Heterogens: NAG, AGH, FUC, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4en3A (A:)
    adlsqqgeedpqalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekh
    sgrlrvtldtskksssllitasraadtasyfcatydrgstlgrlyfgrgtqltvwpdiqn
    pdpavyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsava
    wsnksdfacanafnnsiipedtffpspesssrgglevlfq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4en3A (A:)
    qalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgrlrvtldts
    kksssllitasraadtasyfcatydrgstlgrlyfgrgtqltvwpdiqnpdpavyqlrds
    ksvclftdfdsqtnvsqskdvyitdkcvldmrmdfksnsavawsnksdacanafnnsiip
    edtffp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4en3B (B:)
    adpeadiyqtprylvigtgkkitlecsqtmghdkmywyqqdpgmelhlihysygvnstek
    gdlssestvsrirtehfpltlesarpshtsqylcassensgtgriyeqyfgpgtrltvte
    dlknvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpq
    plkeqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqiv
    saeawgradsrgglevlfq
    

    Sequence, based on observed residues (ATOM records): (download)
    >4en3B (B:)
    adiyqtprylvigtgkkitlecsqtmghdkmywyqqdpgmelhlihysygvnstekgdls
    estvsrirtehfpltlesarpshtsqylcassensgtgriyeqyfgpgtrltvtedlknv
    fppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeq
    palndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeaw
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4en3C (C:)
    adpvpqrlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfs
    dqqwetlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafq
    gkdilsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgks
    elkkqvkpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpna
    detwylratldvvageaaglscrvkhsslegqdivlywhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4en3C (C:)
    fplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwetlq
    hifrvyrssftrdvkefakmlrlsyplelqvsagcevhpasnnffhvafqgkdilsfqgt
    sweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqvkpka
    wlsrgpsplllvchvsgfypkpvwvkwmrqqgtqpgdilpnadetwylratldvvaagls
    crvkhsslegqdivlyw
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4en3D (D:)
    piqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4en3D (D:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm