PDB entry 4emv

View 4emv on RCSB PDB site
Description: Crystal structure of a topoisomerase ATP inhibitor
Class: isomerase/isomerase inhibitor
Keywords: protein-inhibitor complex, ATP binding, structure-based drug design, antimicrobial, virtual screen, ISOMERASE-ISOMERASE INHIBITOR complex
Deposited on 2012-04-12, released 2012-08-01
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-08-01, with a file datestamp of 2012-07-27.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.191
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA topoisomerase IV, B subunit
    Species: Streptococcus pneumoniae GA47373 [TaxId:760835]
    Gene: ParE, SPAR94_0831
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4emva_
  • Heterogens: 0R9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4emvA (A:)
mskkeininnynddaiqvlegldavrkrpgmyigstdgaglhhlvweivdnavdealsgf
gdridvtinkdgsltvqdhgrgmptgmhamgiptveviftilhaggkfgqggyktsgglh
gvgssvvnalsswleveitrdgavykqrfenggkpvttlkkigtalksktgtkvtfmpda
tifsttdfkyntiserlnesafllknvtlsltdkrtdeaiefhyen

    Sequence, based on observed residues (ATOM records): (download) 
    >4emvA (A:)
qvlegldavrkrpgmyigstdgaglhhlvweivdnavdealsgfgdridvtinkdgsltv
qdhgrgmptgmhamgiptveviftilhglhgvgssvvnalsswleveitrdgavykqrfe
nggkpvttlkkigtalksktgtkvtfmpdatifsttdfkyntiserlnesafllknvtls
ltdkrtdeaiefhyen