PDB entry 4eks

View 4eks on RCSB PDB site
Description: T4 Lysozyme L99A/M102H with Isoxazole Bound
Class: hydrolase
Keywords: Hydrolase, Alkylation of Cys97
Deposited on 2012-04-09, released 2012-09-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-10-17, with a file datestamp of 2012-10-12.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: 0.172
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lysozyme
    Species: Enterobacteria phage T4 [TaxId:10665]
    Gene: E
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00720 (23-186)
      • expression tag (12-22)
      • engineered mutation (43)
      • engineered mutation (60)
      • engineered mutation (121)
      • engineered mutation (124)
      • engineered mutation (130)
      • engineered mutation (139)
      • engineered mutation (164)
      • engineered mutation (166)
    Domains in SCOPe 2.08: d4eksa1, d4eksa2
  • Chain 'B':
    Compound: lysozyme
    Species: Enterobacteria phage T4 [TaxId:10665]
    Gene: E
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00720 (23-186)
      • expression tag (13-22)
      • engineered mutation (43)
      • engineered mutation (60)
      • engineered mutation (121)
      • engineered mutation (124)
      • engineered mutation (130)
      • engineered mutation (139)
      • engineered mutation (164)
      • engineered mutation (166)
    Domains in SCOPe 2.08: d4eksb1, d4eksb2
  • Heterogens: BME, 0R1, SO4, ACT, HED, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4eksA (A:)
mghhhhhhdydipttenlyfqgsmnifemlrideglrlkiykdcegyytigighlltksp
dlnaakseldkaigrncngvitkdeaeklfnqdvdaavrgilrnaklkpvydsldavrrc
aainhvfqmgvtgvagftnvlrmlqqkrwdeaavnlaksrwynqcpdrakrvittfrtgt
wdayknl

    Sequence, based on observed residues (ATOM records): (download) 
    >4eksA (A:)
pttenlyfqgsmnifemlrideglrlkiykdcegyytigighlltkspdlnaakseldka
igrncngvitkdeaeklfnqdvdaavrgilrnaklkpvydsldavrrcaainhvfqmgvt
gvagftnvlrmlqqkrwdeaavnlaksrwynqcpdrakrvittfrtgtwdayknl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4eksB (B:)
mghhhhhhdydipttenlyfqgsmnifemlrideglrlkiykdcegyytigighlltksp
dlnaakseldkaigrncngvitkdeaeklfnqdvdaavrgilrnaklkpvydsldavrrc
aainhvfqmgvtgvagftnvlrmlqqkrwdeaavnlaksrwynqcpdrakrvittfrtgt
wdayknl

    Sequence, based on observed residues (ATOM records): (download) 
    >4eksB (B:)
ttenlyfqgsmnifemlrideglrlkiykdcegyytigighlltkspdlnaakseldkai
grncngvitkdeaeklfnqdvdaavrgilrnaklkpvydsldavrrcaainhvfqmgvtg
vagftnvlrmlqqkrwdeaavnlaksrwynqcpdrakrvittfrtgtwdayknl