PDB entry 4ek8
View 4ek8 on RCSB PDB site
Description: Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor
Class: transferase/transferase inhibitor
Keywords: ALPHA AND BETA PROTEIN (A+B), TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2012-04-09, released
2013-05-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-05-29, with a file datestamp of
2013-05-24.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.184
AEROSPACI score: 0.55
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cyclin-dependent kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: CDK2, CDKN2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4ek8a_ - Heterogens: 16K, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4ek8A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>4ek8A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirpstaireisllkelnhpnivklld
vihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdl
kpqnllintegaikladfglarafevvtlwyrapeillgckyystavdiwslgcifaemv
trralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvpplde
dgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl