PDB entry 4eiz

View 4eiz on RCSB PDB site
Description: Structure of Nb113 bound to apoDHFR
Class: oxidoreductase/immune system
Keywords: NADP BINDING, OXIDOREDUCTASE-IMMUNE SYSTEM complex
Deposited on 2012-04-06, released 2013-04-24
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-10-30, with a file datestamp of 2013-10-25.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.173
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Escherichia coli [TaxId:83333]
    Gene: folA, tmrA, b0048, JW0047
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4eiza_
  • Chain 'B':
    Compound: dihydrofolate reductase
    Species: Escherichia coli [TaxId:83333]
    Gene: folA, tmrA, b0048, JW0047
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4eizb_
  • Chain 'C':
    Compound: Nb113 Camel antibody fragment
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4EIZ
    Domains in SCOPe 2.05: d4eizc_
  • Chain 'D':
    Compound: Nb113 Camel antibody fragment
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4EIZ
    Domains in SCOPe 2.05: d4eizd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4eizA (A:)
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4eizB (B:)
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4eizC (C:)
qvqlqesggglvqaggslrlsctasgrtfssyamgwfrqtpgkerefvaaitwggsttly
adsvkgrftmsrdnakntvylqmnslkpedtavyycaadgsqyrstysfrdkpdygswgq
gtqvtvsshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4eizC (C:)
vqlqesggglvqaggslrlsctasgrtfssyamgwfrqtpgkerefvaaitwggsttlya
dsvkgrftmsrdnakntvylqmnslkpedtavyycaadgsqyrstysfrdkpdygswgqg
tqvtvss

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4eizD (D:)
qvqlqesggglvqaggslrlsctasgrtfssyamgwfrqtpgkerefvaaitwggsttly
adsvkgrftmsrdnakntvylqmnslkpedtavyycaadgsqyrstysfrdkpdygswgq
gtqvtvsshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4eizD (D:)
vqlqesggglvqaggslrlsctasgrtfssyamgwfrqtpgkerefvaaitwggsttlya
dsvkgrftmsrdnakntvylqmnslkpedtavyycaadgsqyrstysfrdkpdygswgqg
tqvtvss