PDB entry 4ehm

View 4ehm on RCSB PDB site
Description: RabGGTase in complex with covalently bound Psoromic acid
Class: transferase/transferase inhibitor
Keywords: prenylation, inhibition, Psoromic acid, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-04-02, released 2012-05-30
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-05-30, with a file datestamp of 2012-05-25.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.189
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Geranylgeranyl transferase type-2 subunit alpha
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Ggta, Rabggta
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08602 (0-236)
    • Uniprot Q08602 (241-329)
      • linker (237-240)
  • Chain 'B':
    Compound: Geranylgeranyl transferase type-2 subunit beta
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Ggtb, Rabggtb
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ehmb_
  • Heterogens: PJA, ZN, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ehmB (B:)
gtqqkdvtiksdapdtlllekhadyiasygskkddyeycmseylrmsgvywgltvmdlmg
qlhrmnkeeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvva
yvqslqkedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggf
gcrpgseshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcy
swwvlaslkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsll
geeqikpvspvfcmpeevlqrvnvqpelvs

    Sequence, based on observed residues (ATOM records): (download) 
    >4ehmB (B:)
qkdvtiksdapdtlllekhadyiasygsddyeycmseylrmsgvywgltvmdlmgqlhrm
nkeeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvvayvqsl
qkedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggfgcrpg
seshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcyswwvl
aslkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsllgeeqi
kpvspvfcmpeevlqrvnvqpelvs