PDB entry 4eh4

View 4eh4 on RCSB PDB site
Description: Human p38 MAP kinase in complex with NP-F3 and RL87
Class: Transferase/Transferase inhibitor
Keywords: MAP Kinase Insert, Kinase-Ligand Complex, NP-Fragment, Transferase-Transferase inhibitor complex
Deposited on 2012-04-02, released 2012-12-05
The last revision prior to the SCOPe 2.02 freeze date was dated 2013-01-02, with a file datestamp of 2012-12-28.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.234
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4eh4a_
  • Heterogens: IRG, 0OL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4eh4A (A:)
gsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemt
gyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvg
tpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaa
qalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >4eh4A (A:)
erptfyrqelnktiwevperyqnlspvgsygsvcaafdtktglrvavkklsrpfqsiiha
krtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkkltddhv
qfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglavatrwyrapeimlnw
mhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarn
yiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpdde
pvadpydqsfesrdllidewksltydevisfvpppld