PDB entry 4eg3
View 4eg3 on RCSB PDB site
Description: Trypanosoma brucei methionyl-tRNA synthetase in complex with product methionyl-adenylate
Class: ligase
Keywords: aminoacyl-tRNA synthetase, aaRS, MetRS, parasite, ligase, protein-inhibitor complex, Rossmann-fold, translation, nucleotide binding,, Rossmann Fold, tRNA binding ATP binding
Deposited on
2012-03-30, released
2012-09-12
The last revision prior to the SCOPe 2.04 freeze date was dated
2012-10-31, with a file datestamp of
2012-10-26.
Experiment type: XRAY
Resolution: 2.94 Å
R-factor: 0.214
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Methionyl-tRNA synthetase, putative
Species: Trypanosoma brucei brucei [TaxId:999953]
Gene: Tb10.70.6470
Database cross-references and differences (RAF-indexed):
- Uniprot Q38C91
- conflict (77)
- engineered mutation (220-222)
- conflict (267)
- conflict (271)
- Chain 'B':
Compound: Methionyl-tRNA synthetase, putative
Species: Trypanosoma brucei brucei [TaxId:999953]
Gene: Tb10.70.6470
Database cross-references and differences (RAF-indexed):
- Uniprot Q38C91 (5-End)
- expression tag (0-4)
- conflict (77)
- engineered mutation (220-222)
- conflict (267)
- conflict (271)
Domains in SCOPe 2.04: d4eg3b1, d4eg3b2 - Heterogens: GOL, ME8, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4eg3B (B:)
gpgsmkvekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgq
kvaeaakqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqk
gdiylgryegwysisdesfltpqnitdgvdkdgnpckvslesghvvtwvseenymfrlsa
frerllewyhanpgcivpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcv
yvwldaltnyltgsrlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafl
lsaglplpkkivahgwwtkdrkkiskslgnvfdpvekaeefgydalkyfllresgfsddg
dysdknmiarlngeladtlgnlvmrctsakinvngewpspaayteedesliqlikdlpgt
adhyylipdiqkaiiavfdvlrainayvtdmapwklvktdperlrtvlyitlegvrvttl
llspilprksvvifdmlgvpevhrkgienfefgavppgtrlgpavegevlfskrstentk
st
Sequence, based on observed residues (ATOM records): (download)
>4eg3B (B:)
gpgsmkvekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgq
kvaeaakqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqk
gdiylgryegwysisdesfltpqnitdgvdckvslesghvvtwvseenymfrlsafrerl
lewyhanpgcivpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcvyvwld
altnyltgsrlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafllsagl
plpkkivahgwwtkdrkkisknvfdpvekaeefgydalkyfllresgfsddgdysdknmi
arlngeladtlgnlvmrctsakinvngewpspaayteedesliqlikdlpgtadhyylip
diqkaiiavfdvlrainayvtdmapwklvktdperlrtvlyitlegvrvttlllspilpr
ksvvifdmlgvpevhrkgienfefgavppgtrlgpavegevlfskrste