PDB entry 4eev

View 4eev on RCSB PDB site
Description: Crystal structure of c-Met in complex with LY2801653
Class: transferase/transferase inhibitor
Keywords: protein tyrosine kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-03-28, released 2013-04-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-09-04, with a file datestamp of 2013-08-30.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.19
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4eeva_
  • Heterogens: L1X, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4eevA (A:)
mhhhhhhmgdsdisspllqntvhidlsalnpelvqavqhvvigpsslivhfnevigrghf
gcvyhgtlldndgkkihcavkslnritdigevsqfltegiimkdfshpnvlsllgiclrs
egsplvvlpymkhgdlrnfirnethnptvkdligfglqvakgmkylaskkfvhrdlaarn
cmldekftvkvadfglardmydkeyysvhnktgaklpvkwmaleslqtqkfttksdvwsf
gvllwelmtrgappypdvntfditvyllqgrrllqpeycpdplyevmlkcwhpkaemrps
fselvsrisaifstfig

    Sequence, based on observed residues (ATOM records): (download) 
    >4eevA (A:)
pllqntvhidlsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkk
ihcavkslnritdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgd
lrnfirnethnptvkdligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfg
klpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrll
qpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfig