PDB entry 4ee0
View 4ee0 on RCSB PDB site
Description: Crystal structure of hH-PGDS with water displacing inhibitor
Class: Isomerase/Isomerase inhibitor
Keywords: Inhibitor, Solvent replacement, Isomerase-Isomerase inhibitor complex
Deposited on
2012-03-28, released
2012-07-18
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-07-18, with a file datestamp of
2012-07-13.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.197
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hematopoietic prostaglandin d synthase
Species: Homo sapiens [TaxId:9606]
Gene: GSTS, HPGDS, PGDS, PTGDS2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4ee0a1, d4ee0a2 - Chain 'B':
Compound: hematopoietic prostaglandin d synthase
Species: Homo sapiens [TaxId:9606]
Gene: GSTS, HPGDS, PGDS, PTGDS2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4ee0b1, d4ee0b2, d4ee0b3 - Heterogens: MG, 0O4, GSF, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4ee0A (A:)
hpnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdglt
lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
vqaipavanwikrrpqtkl
Sequence, based on observed residues (ATOM records): (download)
>4ee0A (A:)
pnykltyfnmrgraeiiryifayldiqyedhriepeikstlpfgkipilevdgltlhqsl
aiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnelltynap
hlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkkvqaip
avanwikrrpqtkl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4ee0B (B:)
hpnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdglt
lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
vqaipavanwikrrpqtkl
Sequence, based on observed residues (ATOM records): (download)
>4ee0B (B:)
hpnykltyfnmrgraeiiryifayldiqyedhriadwpeikstlpfgkipilevdgltlh
qslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaeqdvkeqmfnelltyna
phlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkkvqai
pavanwikrrpqtkl