PDB entry 4eb9
View 4eb9 on RCSB PDB site
Description: cIAP1-BIR3 in complex with a divalent Smac mimetic
Class: apoptosis inhibitor
Keywords: zinc finger, APOPTOSIS INHIBITOR
Deposited on
2012-03-23, released
2012-12-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-12-05, with a file datestamp of
2012-11-30.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.26
AEROSPACI score: 0.25
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Baculoviral IAP repeat-containing protein 2
Species: Homo sapiens [TaxId:9606]
Gene: BIRC2, API1, IAP2, MIHB, RNF48
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4eb9a_ - Chain 'B':
Compound: Baculoviral IAP repeat-containing protein 2
Species: Homo sapiens [TaxId:9606]
Gene: BIRC2, API1, IAP2, MIHB, RNF48
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4eb9b_ - Chain 'C':
Compound: Baculoviral IAP repeat-containing protein 2
Species: Homo sapiens [TaxId:9606]
Gene: BIRC2, API1, IAP2, MIHB, RNF48
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4eb9c1, d4eb9c2 - Chain 'D':
Compound: Baculoviral IAP repeat-containing protein 2
Species: Homo sapiens [TaxId:9606]
Gene: BIRC2, API1, IAP2, MIHB, RNF48
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4eb9d1, d4eb9d2 - Heterogens: ZN, 0O6, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4eb9A (A:)
mensletlrfsisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfcc
dgglrcwesgddpwvehakwfprceflirmkgqefvdeiqgryphlleqllstslehhhh
hh
Sequence, based on observed residues (ATOM records): (download)
>4eb9A (A:)
sisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdgglrcwesg
ddpwvehakwfprceflirmkgqefvdeiqgryphlleqlls
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4eb9B (B:)
mensletlrfsisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfcc
dgglrcwesgddpwvehakwfprceflirmkgqefvdeiqgryphlleqllstslehhhh
hh
Sequence, based on observed residues (ATOM records): (download)
>4eb9B (B:)
sisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdgglrcwesg
ddpwvehakwfprceflirmkgqefvdeiqgryphlleqll
- Chain 'C':
Sequence, based on SEQRES records: (download)
>4eb9C (C:)
mensletlrfsisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfcc
dgglrcwesgddpwvehakwfprceflirmkgqefvdeiqgryphlleqllstslehhhh
hh
Sequence, based on observed residues (ATOM records): (download)
>4eb9C (C:)
isnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdgglrcwesgd
dpwvehakwfprceflirmkgqefvdeiqgryphlleqllst
- Chain 'D':
Sequence, based on SEQRES records: (download)
>4eb9D (D:)
mensletlrfsisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfcc
dgglrcwesgddpwvehakwfprceflirmkgqefvdeiqgryphlleqllstslehhhh
hh
Sequence, based on observed residues (ATOM records): (download)
>4eb9D (D:)
sisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdgglrcwesg
ddpwvehakwfprceflirmkgqefvdeiqgryphlleqllst