PDB entry 4eb9

View 4eb9 on RCSB PDB site
Description: cIAP1-BIR3 in complex with a divalent Smac mimetic
Class: apoptosis inhibitor
Keywords: zinc finger, APOPTOSIS INHIBITOR
Deposited on 2012-03-23, released 2012-12-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-12-05, with a file datestamp of 2012-11-30.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.26
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Baculoviral IAP repeat-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: BIRC2, API1, IAP2, MIHB, RNF48
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4eb9a_
  • Chain 'B':
    Compound: Baculoviral IAP repeat-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: BIRC2, API1, IAP2, MIHB, RNF48
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4eb9b_
  • Chain 'C':
    Compound: Baculoviral IAP repeat-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: BIRC2, API1, IAP2, MIHB, RNF48
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4eb9c1, d4eb9c2
  • Chain 'D':
    Compound: Baculoviral IAP repeat-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: BIRC2, API1, IAP2, MIHB, RNF48
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4eb9d1, d4eb9d2
  • Heterogens: ZN, 0O6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4eb9A (A:)
    mensletlrfsisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfcc
    dgglrcwesgddpwvehakwfprceflirmkgqefvdeiqgryphlleqllstslehhhh
    hh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4eb9A (A:)
    sisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdgglrcwesg
    ddpwvehakwfprceflirmkgqefvdeiqgryphlleqlls
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4eb9B (B:)
    mensletlrfsisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfcc
    dgglrcwesgddpwvehakwfprceflirmkgqefvdeiqgryphlleqllstslehhhh
    hh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4eb9B (B:)
    sisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdgglrcwesg
    ddpwvehakwfprceflirmkgqefvdeiqgryphlleqll
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4eb9C (C:)
    mensletlrfsisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfcc
    dgglrcwesgddpwvehakwfprceflirmkgqefvdeiqgryphlleqllstslehhhh
    hh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4eb9C (C:)
    isnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdgglrcwesgd
    dpwvehakwfprceflirmkgqefvdeiqgryphlleqllst
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4eb9D (D:)
    mensletlrfsisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfcc
    dgglrcwesgddpwvehakwfprceflirmkgqefvdeiqgryphlleqllstslehhhh
    hh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4eb9D (D:)
    sisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdgglrcwesg
    ddpwvehakwfprceflirmkgqefvdeiqgryphlleqllst