PDB entry 4eam

View 4eam on RCSB PDB site
Description: 1.70A resolution structure of apo beta-glycosidase (W33G) from sulfolobus solfataricus
Class: hydrolase
Keywords: GLYCOSIDE HYDROLASE, Chemical biology, allosteric activation, switchable enzyme, chemical rescue, HYDROLASE
Deposited on 2012-03-22, released 2012-06-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-galactosidase
    Species: Sulfolobus solfataricus P2 [TaxId:273057]
    Gene: lacS, SSO3019
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22498 (0-488)
      • engineered mutation (32)
    Domains in SCOPe 2.07: d4eama_
  • Chain 'B':
    Compound: beta-galactosidase
    Species: Sulfolobus solfataricus P2 [TaxId:273057]
    Gene: lacS, SSO3019
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22498 (0-488)
      • engineered mutation (32)
    Domains in SCOPe 2.07: d4eamb_
  • Heterogens: CL, MPD, TRS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4eamA (A:)
mysfpnsfrfgwsqagfqsemgtpgsedpntdgykwvhdpenmaaglvsgdlpengpgyw
gnyktfhdnaqkmglkiarlnvewsrifpnplprpqnfdeskqdvteveinenelkrlde
yankdalnhyreifkdlksrglyfilnmyhwplplwlhdpirvrrgdftgpsgwlstrtv
yefarfsayiawkfddlvdeystmnepnvvgglgyvgvksgfppgylsfelsrramynii
qaharaydgiksvskkpvgiiyanssfqpltdkdmeavemaendnrwwffdaiirgeitr
gnekivrddlkgrldwigvnyytrtvvkrtekgyvslggyghgcernsvslaglptsdfg
weffpeglydvltkywnryhlymyvtengiaddadyqrpyylvshvyqvhrainsgadvr
gylhwsladnyewasgfsmrfgllkvdyntkrlywrpsalvyreiatngaitdeiehlns
vppvkplrh

    Sequence, based on observed residues (ATOM records): (download) 
    >4eamA (A:)
mysfpnsfrfgwsqagfqsemgtpgsedpntdgykwvhdpenmaaglvsgdlpengpgyw
gnyktfhdnaqkmglkiarlnvewsrifpnplprpfdeskqdvteveinenelkrldeya
nkdalnhyreifkdlksrglyfilnmyhwplplwlhdpirvrrgdftgpsgwlstrtvye
farfsayiawkfddlvdeystmnepnvvgglgyvgvksgfppgylsfelsrramyniiqa
haraydgiksvskkpvgiiyanssfqpltdkdmeavemaendnrwwffdaiirgeitkiv
rddlkgrldwigvnyytrtvvkrtekgyvslggyghgcernsvslaglptsdfgweffpe
glydvltkywnryhlymyvtengiaddadyqrpyylvshvyqvhrainsgadvrgylhws
ladnyewasgfsmrfgllkvdyntkrlywrpsalvyreiatngaitdeiehlnsvppvkp
lrh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4eamB (B:)
mysfpnsfrfgwsqagfqsemgtpgsedpntdgykwvhdpenmaaglvsgdlpengpgyw
gnyktfhdnaqkmglkiarlnvewsrifpnplprpqnfdeskqdvteveinenelkrlde
yankdalnhyreifkdlksrglyfilnmyhwplplwlhdpirvrrgdftgpsgwlstrtv
yefarfsayiawkfddlvdeystmnepnvvgglgyvgvksgfppgylsfelsrramynii
qaharaydgiksvskkpvgiiyanssfqpltdkdmeavemaendnrwwffdaiirgeitr
gnekivrddlkgrldwigvnyytrtvvkrtekgyvslggyghgcernsvslaglptsdfg
weffpeglydvltkywnryhlymyvtengiaddadyqrpyylvshvyqvhrainsgadvr
gylhwsladnyewasgfsmrfgllkvdyntkrlywrpsalvyreiatngaitdeiehlns
vppvkplrh

    Sequence, based on observed residues (ATOM records): (download) 
    >4eamB (B:)
mysfpnsfrfgwsqagfqsemgtpgsedpntdgykwvhdpenmaaglvsgdlpengpgyw
gnyktfhdnaqkmglkiarlnvewsrifpnplprpfdeskqdvteveinenelkrldeya
nkdalnhyreifkdlksrglyfilnmyhwplplwlhdpirvrrgdftgpsgwlstrtvye
farfsayiawkfddlvdeystmnepnvvgglgyvgvksgfppgylsfelsrramyniiqa
haraydgiksvskkpvgiiyanssfqpltdkdmeavemaendnrwwffdaiirgeitrki
vrddlkgrldwigvnyytrtvvkrtekgyvslggyghgcernsvslaglptsdfgweffp
eglydvltkywnryhlymyvtengiaddadyqrpyylvshvyqvhrainsgadvrgylhw
sladnyewasgfsmrfgllkvdyntkrlywrpsalvyreiatngaitdeiehlnsvppvk
plrh