PDB entry 4eag

View 4eag on RCSB PDB site
Description: Co-crystal structure of an chimeric AMPK core with ATP
Class: transferase
Keywords: ampk, transferase
Deposited on 2012-03-22, released 2012-06-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-03-12, with a file datestamp of 2014-03-07.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.211
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: EG:132E8.2 protein
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: SNF1A, EG:132E8.2, SNF1A-RA, CG3051, Dmel_CG3051
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4eaga_
  • Chain 'B':
    Compound: 5'-AMP-activated protein kinase subunit beta-1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Prkab1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80386 (1-84)
      • expression tag (0)
  • Chain 'C':
    Compound: 5'-amp-activated protein kinase subunit gamma-1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Prkag1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4eagc1, d4eagc2
  • Heterogens: ATP, TAM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4eagA (A:)
gphmgakwhlgirsqskpndimlevyramkalsyewkiinpyhvrvrrqnvktgkfskms
lqlyqvdaksylldfksltndeveqgddvimesltppplsvsgvmplqptghhtmeffem
caaliiqlar

    Sequence, based on observed residues (ATOM records): (download) 
    >4eagA (A:)
akwhlgirsqskpndimlevyramkalsyewkiinpyhvrvrrqnvktgkfskmslqlyq
vdaksylldfksltlqptghhtmeffemcaaliiqlar

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4eagC (C:)
mesvaaesapapenehsqetpesnssvyttfmkshrcydliptssklvvfdtslqvkkaf
falvtngvraaplwdskkqsfvgmltitdfinilhryyksalvqiyeleehkietwrevy
lqdsfkplvcispnaslfdavsslirnkihrlpvidpesgntlyilthkrilkflklfit
efpkpefmsksleelqigtyaniamvrtttpvyvalgifvqhrvsalpvvdekgrvvdiy
skfdvinlaaektynnldvsvtkalqhrshyfegvlkcylhetleaiinrlveaevhrlv
vvdehdvvkgivslsdilqalvltggekkp

    Sequence, based on observed residues (ATOM records): (download) 
    >4eagC (C:)
svyttfmkshrcydliptssklvvfdtslqvkkaffalvtngvraaplwdskkqsfvgml
titdfinilhryyksalvqiyeleehkietwrevylqdsfkplvcispnaslfdavssli
rnkihrlpvidpesgntlyilthkrilkflklfitefpkpefmsksleelqigtyaniam
vrtttpvyvalgifvqhrvsalpvvdekgrvvdiyskfdvinlaanldvsvtkalqhrgv
lkcylhetleaiinrlveaevhrlvvvdehdvvkgivslsdilqalvlt