PDB entry 4e96
View 4e96 on RCSB PDB site
Description: Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor PFi-1
Class: protein binding/inhibitor
Keywords: BROMODOMAIN,CAP, HUNK1, MCAP, MITOTIC CHROMOSOME ASSOCIATED PROTEIN, JQ1, BETSOFF1, STRUCTURAL GENOMICS CONSORTIUM, SGC, CELL CYCLE, PROTEIN BINDING-INHIBITOR complex
Deposited on
2012-03-20, released
2012-04-18
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-02-27, with a file datestamp of
2013-02-22.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: 0.216
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4e96a1, d4e96a2 - Heterogens: 0NS, NA, DMS, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4e96A (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee
Sequence, based on observed residues (ATOM records): (download)
>4e96A (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelp