PDB entry 4e4a
View 4e4a on RCSB PDB site
Description: Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
Class: lyase/lyase inhibitor
Keywords: Carbonate dehydratase, Inhibitor, LYASE-LYASE INHIBITOR complex
Deposited on
2012-03-12, released
2012-06-27
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-06-27, with a file datestamp of
2012-06-22.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: 0.187
AEROSPACI score: 0.65
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Carbonic anhydrase 2
Species: Homo sapiens [TaxId:9606]
Gene: CA2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4e4aa_ - Heterogens: ZN, JKE, MBO, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4e4aA (A:)
mshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslril
nnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhl
vhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdp
rgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelm
vdnwrpaqplknrqikasfk
Sequence, based on observed residues (ATOM records): (download)
>4e4aA (A:)
hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
hafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvhw
ntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprgl
lpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvdn
wrpaqplknrqikasfk