PDB entry 4e2v

View 4e2v on RCSB PDB site
Description: tRNA-guanine transglycosylase Y106F, C158V mutant in complex with preQ1
Class: transferase/transferase inhibitor
Keywords: substrate specificity, bacterial TGT, guanin, tRNA, preQ1, guanine exchange enzyme, transferase-transferase inhibitor complex
Deposited on 2012-03-09, released 2013-03-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.18 Å
R-factor: N/A
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis [TaxId:542]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • engineered mutation (105)
      • engineered mutation (157)
      • see remark 999 (311)
    Domains in SCOPe 2.08: d4e2va_
  • Heterogens: PRF, GOL, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4e2vA (A:)
mveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvr
atgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggfqvmslssltkqsee
gvtfkshldgsrhmlspersieiqhllgsdivmafdevtpypatpsraassmersmrwak
rsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqdem
frvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpi
nirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqk
irdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >4e2vA (A:)
rprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvratgadiilgn
tyhlmlrpgaeriaklgglhsfmgwdrpiltdsggfqvmkqseegvtfkshsrhmlsper
sieiqhllgsdivmafdevtpypatpsraassmersmrwakrsrdafdsrkeqaenaalf
giqqgsvfenlrqqsadalaeigfdgyavgglavgegqdemfrvldfsvpmlpddkphyl
mgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpinirnarfsedlkpldsech
cavcqkwsrayihhlirageilgamlmtehniafyqqlmqkirdsisegrfsqfaqdfra
ryfa