PDB entry 4e1n

View 4e1n on RCSB PDB site
Description: Crystal Structure of HIV-1 Integrase with a non-catayltic site inhibitor
Class: transferase/transferase inhibitor
Keywords: HIV-1, integrase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-03-06, released 2012-04-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-07-25, with a file datestamp of 2012-07-20.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.243
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-1 integrase
    Species: Human immunodeficiency virus type 1 [TaxId:11698]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497
      • conflict (77)
      • engineered mutation (138)
    Domains in SCOPe 2.07: d4e1na_
  • Heterogens: TQX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4e1nA (A:)
gshmhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklag
rwpvktvhtdngsnftsatvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvr
dqaehlktavqmavfihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >4e1nA (A:)
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsatvkaacwwagikqefgipnpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnkkrkysagerivdiiatd