PDB entry 4dro
View 4dro on RCSB PDB site
Description: EVALUATION OF SYNTHETIC FK506 ANALOGS AS LIGANDS FOR FKBP51 AND FKBP52: COMPLEX OF FKBP51 WITH (1R)-3-(3,4-dimethoxyphenyl)-1-phenylpropyl (2S)-1-{[(1R,2S)-2-ethyl-1-hydroxycyclohexyl](oxo)acetyl}piperidine-2-carboxylate
Class: isomerase
Keywords: Fk-506 binding domain, Hsp90 cochaperone, immunophilin, peptidyl-prolyl isomerase, ISOMERASE
Deposited on
2012-02-17, released
2012-05-16
The last revision prior to the SCOPe 2.03 freeze date was dated
2012-05-23, with a file datestamp of
2012-05-18.
Experiment type: XRAY
Resolution: 1.1 Å
R-factor: 0.149
AEROSPACI score: 0.91
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Peptidyl-prolyl cis-trans isomerase FKBP5
Species: Homo sapiens [TaxId:9606]
Gene: AIG6, FKBP5, FKBP51
Database cross-references and differences (RAF-indexed):
- Uniprot Q13451 (3-127)
- expression tag (0-2)
- conflict (6)
Domains in SCOPe 2.03: d4droa_ - Heterogens: 0MD, HOH