PDB entry 4dqf
View 4dqf on RCSB PDB site
Description: Crystal Structure of (G16A/L38A) HIV-1 Protease in Complex with DRV
Class: hydrolase/hydrolase inhibitor
Keywords: HIV-1 protease, drug resistance, drug design, Protease inhibitors, AIDS, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2012-02-15, released
2012-03-07
The last revision prior to the SCOPe 2.04 freeze date was dated
2012-05-02, with a file datestamp of
2012-04-27.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.186
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Aspartyl protease
Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
Gene: gag-pol
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4dqfa_ - Chain 'B':
Compound: Aspartyl protease
Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
Gene: gag-pol
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4dqfb_ - Heterogens: 017, SO4, EDO, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4dqfA (A:)
pqitlwkrplvtiriagqlkealldtgaddtvieemnapgkwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf
Sequence, based on observed residues (ATOM records): (download)
>4dqfA (A:)
pqitlwkrplvtiriagqlkealldtgaddtvieeapgkwkpkmiggiggfikvrqydqi
iieiaghkaigtvlvgptpvniigrnlltqigatlnf
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4dqfB (B:)
pqitlwkrplvtiriagqlkealldtgaddtvieemnapgkwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf