PDB entry 4dnk

View 4dnk on RCSB PDB site
Description: Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB) from homo sapiens at 2.20 A resolution.
Class: signaling protein
Keywords: 14-3-3 domain, phosphorylation, protein-protein binding, cell signaling, cell regulation, Structural Genomics, Joint Center for Structural Genomics, JCSG, Protein Structure Initiative, PSI-BIOLOGY, SIGNALING PROTEIN
Deposited on 2012-02-08, released 2012-02-22
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-05-23, with a file datestamp of 2012-05-18.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.194
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 14-3-3 protein beta/alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: BC001359, YWHAB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4dnka_
  • Chain 'B':
    Compound: 14-3-3 protein beta/alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: BC001359, YWHAB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4dnkb_
  • Heterogens: PO4, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4dnkA (A:)
gmtmdkselvqkaklaeqaeryddmaaamkavteqghelsneernllsvayknvvgarrs
swrvissieqkternekkqqmgkeyrekieaelqdicndvlelldkylipnatqpeskvf
ylkmkgdyfrylsevasgdnkqttvsnsqqayqeafeiskkemqpthpirlglalnfsvf
yyeilnspekacslaktafdeaiaeldtlneesykdstlimqllrdnltlwtsenqgdeg
dagegen

    Sequence, based on observed residues (ATOM records): (download) 
    >4dnkA (A:)
tmdkselvqkaklaeqaeryddmaaamkavteqghelsneernllsvayknvvgarrssw
rvissieqkternekkqqmgkeyrekieaelqdicndvlelldkylipnatqpeskvfyl
kmkgdyfrylsevasgdnkqttvsnsqqayqeafeiskkemqpthpirlglalnfsvfyy
eilnspekacslaktafdeaiaeldtlneesykdstlimqllrdnltlwtse

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4dnkB (B:)
gmtmdkselvqkaklaeqaeryddmaaamkavteqghelsneernllsvayknvvgarrs
swrvissieqkternekkqqmgkeyrekieaelqdicndvlelldkylipnatqpeskvf
ylkmkgdyfrylsevasgdnkqttvsnsqqayqeafeiskkemqpthpirlglalnfsvf
yyeilnspekacslaktafdeaiaeldtlneesykdstlimqllrdnltlwtsenqgdeg
dagegen

    Sequence, based on observed residues (ATOM records): (download) 
    >4dnkB (B:)
mtmdkselvqkaklaeqaeryddmaaamkavteqghelsneernllsvayknvvgarrss
wrvissieqkternekkqqmgkeyrekieaelqdicndvlelldkylipnatqpeskvfy
lkmkgdyfrylsevasgdnkqttvsnsqqayqeafeiskkemqpthpirlglalnfsvfy
yeilnspekacslaktafdeaiaeldtlneesykdstlimqllrdnltlwtsen