PDB entry 4dm9

View 4dm9 on RCSB PDB site
Description: The Crystal Structure of Ubiquitin Carboxy-terminal hydrolase L1 (UCHL1) bound to a tripeptide fluoromethyl ketone Z-VAE(OMe)-FMK
Class: hydrolase, ligase/inhibitor
Keywords: Ubiquitin Hydrolase, Ligase, HYDROLASE, LIGASE-INHIBITOR complex
Deposited on 2012-02-07, released 2012-05-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-06-13, with a file datestamp of 2012-06-08.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.2
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase isozyme L1
    Species: Homo sapiens [TaxId:9606]
    Gene: UCHL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4dm9a_
  • Chain 'B':
    Compound: Ubiquitin carboxyl-terminal hydrolase isozyme L1
    Species: Homo sapiens [TaxId:9606]
    Gene: UCHL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4dm9b_
  • Chain 'X':
    Compound: Tripeptide fluoromethyl ketone inhibitor Z-VAE(OMe)-FMK
    Database cross-references and differences (RAF-indexed):
    • PDB 4DM9 (0-4)
  • Chain 'Y':
    Compound: Tripeptide fluoromethyl ketone inhibitor Z-VAE(OMe)-FMK
    Database cross-references and differences (RAF-indexed):
    • PDB 4DM9 (0-4)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4dm9A (A:)
    gplgsmqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpl
    taqhenfrkkqieelkgqevspkvyfmkqtignscgtiglihavannqdklgfedgsvlk
    qflsetekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyel
    dgrmpfpvnhgassedtllkdaakvcreftereqgevrfsavalckaa
    

    Sequence, based on observed residues (ATOM records): (download)
    >4dm9A (A:)
    mqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpltaqhe
    nfrkkqieelkgqevspkvyfmkqtignscgtiglihavannqdklgfedgsvlkqflse
    tekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyeldgrmp
    fpvnhgassedtllkdaakvcreftereqgevrfsavalckaa
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4dm9B (B:)
    gplgsmqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpl
    taqhenfrkkqieelkgqevspkvyfmkqtignscgtiglihavannqdklgfedgsvlk
    qflsetekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyel
    dgrmpfpvnhgassedtllkdaakvcreftereqgevrfsavalckaa
    

    Sequence, based on observed residues (ATOM records): (download)
    >4dm9B (B:)
    mqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpltaqhe
    nfrkkqieelkgqevspkvyfmkqtignscgtiglihavannqdklgfedgsvlkqflse
    tekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyeldgrmp
    fpvnhgassedtllkdaakvcreftereqgevrfsavalckaa
    

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    No sequence available.