PDB entry 4dj9

View 4dj9 on RCSB PDB site
Description: Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50 (VBS50, residues 2078-2099)
Class: Cell Adhesion
Keywords: cytoskeleton, focal adhesion, protein-protein interaction, four-helix bundle, cell adhesion, F-actin, cytosol
Deposited on 2012-02-01, released 2012-02-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-05-16, with a file datestamp of 2012-05-11.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.209
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: vinculin
    Species: Homo sapiens [TaxId:9606]
    Gene: VCL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4dj9a1, d4dj9a2
  • Chain 'B':
    Compound: Talin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: TLN1, KIAA1027, TLN
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4dj9A (A:)
mpvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnlvrvgke
tvqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgilsgts
dllltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderqq
elthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvekmsae
ineiirvlqltswdedaw

    Sequence, based on observed residues (ATOM records): (download) 
    >4dj9A (A:)
vfhtrtiesilepvaqqishlvimheegkaipdltapvaavqaavsnlvrvgketvqtte
dqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgilsgtsdllltf
deaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderqqelthqe
hrvmlvnsmntvkellpvlisamkifvttqgieealknrnftvekmsaeineiirvlqlt
swd

  • Chain 'B':
    No sequence available.