PDB entry 4dgp

View 4dgp on RCSB PDB site
Description: The wild-type Src homology 2 (SH2)-domain containing protein tyrosine phosphatase-2 (SHP2)
Class: hydrolase
Keywords: hydrolase
Deposited on 2012-01-26, released 2013-03-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-05-01, with a file datestamp of 2013-04-26.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.199
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 11
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN11, PTP2C, SHPTP2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4dgpa1, d4dgpa2, d4dgpa3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4dgpA (A:)
mtsrrwfhpnitgveaenllltrgvdgsflarpsksnpgdftlsvrrngavthikiqntg
dyydlyggekfatlaelvqyymehhgqlkekngdvielkyplncadptserwfhghlsgk
eaeklltekgkhgsflvresqshpgdfvlsvrtgddkgesndgkskvthvmircqelkyd
vgggerfdsltdlvehykknpmvetlgtvlqlkqplnttrinaaeiesrvrelsklaett
dkvkqgfweefetlqqqeckllysrkegqrqenknknryknilpfdhtrvvlhdgdpnep
vsdyinaniimpefetkcnnskpkksyiatqgclqntvndfwrmvfqensrvivmttkev
ergkskcvkywpdeyalkeygvmrvrnvkesaahdytlrelklskvgqgntertvwqyhf
rtwpdhgvpsdpggvldfleevhhkqesimdagpvvvhcsagigrtgtfividilidiir
ekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymavqhyietlqrrlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4dgpA (A:)
srrwfhpnitgveaenllltrgvdgsflarpsksnpgdftlsvrrngavthikiqntgdy
ydlyggekfatlaelvqyymehhgqlkekngdvielkyplncadptserwfhghlsgkea
eklltekgkhgsflvresqshpgdfvlsvrtgddkgesndgkskvthvmircqelkydvg
ggerfdsltdlvehykknpmvetlgtvlqlkqplnttrinaaeiesrvrelskgfweefe
tlqqqeckllysrkegqrqenknknryknilpfdhtrvvlhdsdyinaniimpekksyia
tqgclqntvndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeygvmrvrnvk
esaahdytlrelklskvgqgntertvwqyhfrtwpdhgvpsdpggvldfleevhhkqesi
mdagpvvvhcsagigrtgtfividilidiirekgvdcdidvpktiqmvrsqrsgmvqtea
qyrfiymavqhyietlqrr