PDB entry 4dgl

View 4dgl on RCSB PDB site
Description: Crystal Structure of the CK2 Tetrameric Holoenzyme
Class: transferase
Keywords: protein kinase, TRANSFERASE
Deposited on 2012-01-26, released 2012-05-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-01-02, with a file datestamp of 2012-12-28.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.197
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase II subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2B, CK2N, G5A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67870 (Start-214)
      • engineered mutation (124)
    Domains in SCOPe 2.06: d4dgla_
  • Chain 'B':
    Compound: Casein kinase II subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2B, CK2N, G5A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67870
      • engineered mutation (124)
    Domains in SCOPe 2.06: d4dglb_
  • Chain 'C':
    Compound: Casein kinase II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2A1, CK2A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4dglc_
  • Chain 'D':
    Compound: Casein kinase II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2A1, CK2A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4dgld_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4dglA (A:)
mssseevswiswfcglrgneffcevdedyiqdkfnltglneqvphyrqaldmildlepde
elednpnqsdlieqaaemlygliharyiltnrgiaqmlekyqqgdfgycprvycenqpml
piglsdipgeamvklycpkcmdvytpkssrhhhtdgayfgtgfphmlfmvhpeyrpkrpa
nqfvprlygfkihpmayqlqlqaasnfkspvktir

    Sequence, based on observed residues (ATOM records): (download) 
    >4dglA (A:)
swiswfcglrgneffcevdedyiqdkfnltglneqvphyrqaldmildlnpnqsdlieqa
aemlygliharyiltnrgiaqmlekyqqgdfgycprvycenqpmlpiglsdipgeamvkl
ycpkcmdvytpkssrhhhtdgayfgtgfphmlfmvhpeyrpkrpanqfvprlygfkihpm
ayqlqlqaasnfkspvktir

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4dglB (B:)
mssseevswiswfcglrgneffcevdedyiqdkfnltglneqvphyrqaldmildlepde
elednpnqsdlieqaaemlygliharyiltnrgiaqmlekyqqgdfgycprvycenqpml
piglsdipgeamvklycpkcmdvytpkssrhhhtdgayfgtgfphmlfmvhpeyrpkrpa
nqfvprlygfkihpmayqlqlqaasnfkspvktir

    Sequence, based on observed residues (ATOM records): (download) 
    >4dglB (B:)
vswiswfcglrgneffcevdedyiqdkfnltglneqvphyrqaldmildlepdeelednp
nqsdlieqaaemlygliharyiltnrgiaqmlekyqqgdfgycprvycenqpmlpiglsd
ipgeamvklycpkcmdvytpkssrhhhtdgayfgtgfphmlfmvhpeyrpkrpanqfvpr
lygfkihpmayqlqlqaasnf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4dglC (C:)
msgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainit
nnekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntd
fkqlrqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglae
fyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnyd
qlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdf
ldkllrydhqsrltareamehpyfytvvkdqarmg

    Sequence, based on observed residues (ATOM records): (download) 
    >4dglC (C:)
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlrqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqarmg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4dglD (D:)
msgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainit
nnekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntd
fkqlrqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglae
fyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnyd
qlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdf
ldkllrydhqsrltareamehpyfytvvkdqarmg

    Sequence, based on observed residues (ATOM records): (download) 
    >4dglD (D:)
gpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitnn
ekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdfk
qlrqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaefy
hpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydql
vriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfld
kllrydhqsrltareamehpyfytvvkd