PDB entry 4dfr
View 4dfr on RCSB PDB site
Description: crystal structures of escherichia coli and lactobacillus casei dihydrofolate reductase refined at 1.7 angstroms resolution. I. general features and binding of methotrexate
Class: oxidoreductase
Keywords: oxido-reductase, oxidoreductase
Deposited on
1982-06-25, released
1982-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-29, with a file datestamp of
2017-11-24.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.39
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Escherichia coli [TaxId:37762]
Database cross-references and differences (RAF-indexed):
- Uniprot P0ABQ4 (0-158)
- conflict (36)
- conflict (153)
Domains in SCOPe 2.08: d4dfra_ - Chain 'B':
Compound: dihydrofolate reductase
Species: Escherichia coli [TaxId:37762]
Database cross-references and differences (RAF-indexed):
- Uniprot P0ABQ4 (0-158)
- conflict (36)
- conflict (153)
Domains in SCOPe 2.08: d4dfrb_ - Heterogens: CL, MTX, CA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4dfrA (A:)
misliaalavdrvigmenampwnlpadlawfkrntldkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfkilerr
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4dfrB (B:)
misliaalavdrvigmenampwnlpadlawfkrntldkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfkilerr