PDB entry 4ddr
View 4ddr on RCSB PDB site
Description: Human dihydrofolate reductase complexed with NADPH and P218
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: antifolate, NADPH, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on
2012-01-19, released
2012-11-14
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-11-14, with a file datestamp of
2012-11-09.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.205
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Homo sapiens [TaxId:9606]
Gene: Dhfr
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4ddra_ - Heterogens: NDP, MMV, HOH