PDB entry 4d0f
View 4d0f on RCSB PDB site
Description: Human Notch1 EGF domains 11-13 mutant T466A
Class: transcription
Keywords: transcription, metal-binding, transmembrane, developmental, protein, notch signaling pathway, differentiation, phosphorylation, egf-like domain, regulation, receptor, activator, ank repeat, signalling, glycoprotein, extracellular, jagged, nucleus, membrane
Deposited on
2014-04-25, released
2014-05-21
The last revision prior to the SCOPe 2.05 freeze date was dated
2014-06-04, with a file datestamp of
2014-05-30.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.2247
AEROSPACI score: 0.18
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Neurogenic locus notch homolog protein 1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P46531 (2-117)
- expression tag (1)
- expression tag (118-125)
- engineered mutation (57)
Domains in SCOPe 2.05: d4d0fa1, d4d0fa2, d4d0fa3 - Heterogens: CA, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4d0fA (A:)
saqdvdecslganpcehagkcintlgsfecqclqgytgprceidvnecvsnpcqndaacl
dqigefqcicmpgyegvhcevntdecasspclhngrcldkinefqcecptgftghlcqvd
lhhildaqkmvwnhr
Sequence, based on observed residues (ATOM records): (download)
>4d0fA (A:)
aqdvdecslganpcehagkcintlgsfecqclqgytgprceidvnecvsnpcqndaacld
qigefqcicmpgyegvhcevntdecasspclhngrcldkinefqcecptgftghlcqvdl
hhild