PDB entry 4cx7

View 4cx7 on RCSB PDB site
Description: Structure of human iNOS heme domain in complex with (R)-6-(3-AMINO-2-(5-(2-(6-AMINO-4- METHYLPYRIDIN-2-YL)ETHYL)PYRIDIN-3-YL)PROPYL)-4- METHYLPYRIDIN-2-AMINE
Class: oxidoreductase
Keywords: oxidoreductase, inhibitor complex
Deposited on 2014-04-03, released 2014-08-13
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-08-13, with a file datestamp of 2014-08-08.
Experiment type: XRAY
Resolution: 3.16 Å
R-factor: 0.17571
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nitric oxide synthase, inducible
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4cx7a_
  • Chain 'B':
    Compound: Nitric oxide synthase, inducible
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Nitric oxide synthase, inducible
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Nitric oxide synthase, inducible
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HEM, H4B, S71, GOL, SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cx7A (A:)
ldatplssprhvriknwgsgmtfqdtlhhkakgiltcrsksclgsimtpksltrgprdkp
tppdellpqaiefvnqyygsfkeakieehlarveavtkeiettgtyqltgdelifatkqa
wrnaprcigriqwsnlqvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdg
khdfrvwnaqliryagyqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqang
rdpelfeippdlvlevamehpkyewfrelelkwyalpavanmllevgglefpgcpfngwy
mgteigvrdfcdvqrynileevgrrmglethklaslwkdqavveiniavlhsfqkqnvti
mdhhsaaesfmkymqneyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqv
eawkthvwqde

    Sequence, based on observed residues (ATOM records): (download) 
    >4cx7A (A:)
rhvriknwgsgmtfqdtlhhkakgiclgsimtpksltrgprdkptppdellpqaiefvnq
yygsfkeakieehlarveavtkeiettgtyqltgdelifatkqawrnaprcigriqwsnl
qvfdarscstaremfehicrhvrystnngnirsaitvfpqrsdgkhdfrvwnaqliryag
yqmpdgsirgdpanveftqlcidlgwkpkygrfdvvplvlqangrdpelfeippdlvlev
amehpkyewfrelelkwyalpavanmllevgglefpgcpfngwymgteigvrdfcdvqry
nileevgrrmglethklaslwkdqavveiniavlhsfqkqnvtimdhhsaaesfmkymqn
eyrsrggcpadwiwlvppmsgsitpvfhqemlnyvlspfyyyqveawkthvwqd

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.