PDB entry 4cuf
View 4cuf on RCSB PDB site
Description: Human Notch1 EGF domains 11-13 mutant T466S
Class: transcription
Keywords: transcription, metal-binding, transmembrane, developmental, protein, notch signaling pathway, differentiation, phosphorylation, egf-like domain, regulation, receptor, activator, ank repeat, signalling, glycoprotein, extracellular, egf, jagged, nucleus, membrane
Deposited on
2014-03-18, released
2014-05-14
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-02-07, with a file datestamp of
2018-02-02.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Neurogenic locus notch homolog protein 1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P46531 (Start-117)
- expression tag (118-123)
- engineered mutation (57)
Domains in SCOPe 2.08: d4cufa1, d4cufa2, d4cufa3, d4cufa4 - Heterogens: CA, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4cufA (A:)
saqdvdecslganpcehagkcintlgsfecqclqgytgprceidvnecvsnpcqndascl
dqigefqcicmpgyegvhcevntdecasspclhngrcldkinefqcecptgftghlcqvd
lhhildaqkmvwnhr
Sequence, based on observed residues (ATOM records): (download)
>4cufA (A:)
dvdecslganpcehagkcintlgsfecqclqgytgprceidvnecvsnpcqndascldqi
gefqcicmpgyegvhcevntdecasspclhngrcldkinefqcecptgftghlcqvdlhh
i