PDB entry 4cnm

View 4cnm on RCSB PDB site
Description: Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)
Class: cell adhesion
Keywords: cell adhesion, waif1, tpbg, trovax, mva-5t4, cancer, signaling, leucine-rich repeats, wnt/beta-catenin signaling pathway
Deposited on 2014-01-23, released 2014-02-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-04-23, with a file datestamp of 2014-04-18.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.18365
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: trophoblast glycoprotein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13641 (3-End)
      • expression tag (0-2)
    Domains in SCOPe 2.07: d4cnma1, d4cnma2
  • Heterogens: NAG, PEG, CIT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4cnmA (A:)
    etgdqcpalcecseaartvkcvnrnltevptdlpayvrnlfltgnqlavlpagafarrpp
    laelaalnlsgsrldevragafehlpslrqldlshnpladlspfafsgsnasvsapsplv
    elilnhivppederqnrsfegmvvaallagralqglrrlelasnhflylprdvlaqlpsl
    rhldlsnnslvsltyvsfrnlthleslhlednalkvlhngtlaelqglphirvfldnnpw
    vcdchmadmvtwlketevvqgkdrltcaypekmrnrvllelnsadldcdgtetsqvapa
    

    Sequence, based on observed residues (ATOM records): (download)
    >4cnmA (A:)
    etgdqcpalcecseaartvkcvnrnltevptdlpayvrnlfltgnqlavlpagafarrpp
    laelaalnlsgsrldevragafehlpslrqldlshnpladlspfafsgsnpsplveliln
    hivppederqnrsfegmvvaallagralqglrrlelasnhflylprdvlaqlpslrhldl
    snnslvsltyvsfrnlthleslhlednalkvlhngtlaelqglphirvfldnnpwvcdch
    madmvtwlketevvqgkdrltcaypekmrnrvllelnsadldc