PDB entry 4cim

View 4cim on RCSB PDB site
Description: Complex of a Bcl-w BH3 mutant with a BH3 domain
Class: apoptosis
Keywords: apoptosis, cell death
Deposited on 2013-12-12, released 2014-11-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-01-14, with a file datestamp of 2015-01-09.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.1874
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: bcl-2-like protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92843
      • engineered mutation (28)
      • engineered mutation (42)
      • engineered mutation (45)
      • engineered mutation (48)
      • engineered mutation (127)
      • engineered mutation (132)
    Domains in SCOPe 2.08: d4cima_
  • Chain 'B':
    Compound: bcl-2-like protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92843
      • engineered mutation (28)
      • engineered mutation (42)
      • engineered mutation (45)
      • engineered mutation (48)
      • engineered mutation (127)
      • engineered mutation (132)
    Domains in SCOPe 2.08: d4cimb_
  • Chain 'P':
    Compound: bcl-2-like protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92843 (0-20)
      • engineered mutation (5)
      • engineered mutation (8)
      • engineered mutation (11)
  • Chain 'Q':
    Compound: bcl-2-like protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92843 (0-20)
      • engineered mutation (5)
      • engineered mutation (8)
      • engineered mutation (11)
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cimA (A:)
matpasapdtralvadfvgyklrqkgyvsgagpgegpaadplgqalraigdefetrfrrt
fsdlaaqlhvtpgsaqqrftqvsdelfqggpnwgrlvaffvfgaalcaesvnkemeplvg
qvqewmveyletrladwihssggwaeftalygdgaleearrlr

    Sequence, based on observed residues (ATOM records): (download) 
    >4cimA (A:)
apdtralvadfvgyklrqkgyvsgagpgegpaadplgqalraigdefetrfrrtfsdlaa
qlhvtpgsaqqrftqvsdelfqggpnwgrlvaffvfgaalcaesvnkemeplvgqvqewm
veyletrladwihssggwaeftalyg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4cimB (B:)
matpasapdtralvadfvgyklrqkgyvsgagpgegpaadplgqalraigdefetrfrrt
fsdlaaqlhvtpgsaqqrftqvsdelfqggpnwgrlvaffvfgaalcaesvnkemeplvg
qvqewmveyletrladwihssggwaeftalygdgaleearrlr

    Sequence, based on observed residues (ATOM records): (download) 
    >4cimB (B:)
pdtralvadfvgyklrqkgyvsgagpgegpaadplgqalraigdefetrfrrtfsdlaaq
lhvtpgsaqqrftqvsdelfqggpnwgrlvaffvfgaalcaesvnkemeplvgqvqewmv
eyletrladwihssggwaeftalyg

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.