PDB entry 4cfr

View 4cfr on RCSB PDB site
Description: Ca-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with non- muscle myosin IIA
Class: ca-binding protein/motor protein
Keywords: ca-binding protein-motor protein complex, ca-binding, ef-hand
Deposited on 2013-11-19, released 2014-05-07
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-05-28, with a file datestamp of 2014-05-23.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.161
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein S100-A4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26447
      • engineered mutation (5)
      • engineered mutation (83)
      • engineered mutation (47)
      • engineered mutation (88)
    Domains in SCOPe 2.06: d4cfra_
  • Chain 'B':
    Compound: Protein S100-A4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26447 (3-End)
      • engineered mutation (5)
      • engineered mutation (83)
      • engineered mutation (47)
      • engineered mutation (88)
    Domains in SCOPe 2.06: d4cfrb_
  • Chain 'Q':
    Compound: myosin-9
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35579 (0-End)
      • engineered mutation (0)
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cfrA (A:)
gshmasplekaldvmvstfhkysgkegdkfklnkselkelltrelpswlgkrtdeaafqk
lmsnldsnrdnevdfqeycvflssiammsneffegfpdkqprkk

    Sequence, based on observed residues (ATOM records): (download) 
    >4cfrA (A:)
asplekaldvmvstfhkysgkegdkfklnkselkelltrelpswlgkrtdeaafqklmsn
ldsnrdnevdfqeycvflssiammsneffegfpd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4cfrB (B:)
gshmasplekaldvmvstfhkysgkegdkfklnkselkelltrelpswlgkrtdeaafqk
lmsnldsnrdnevdfqeycvflssiammsneffegfpdkqprkk

    Sequence, based on observed residues (ATOM records): (download) 
    >4cfrB (B:)
masplekaldvmvstfhkysgkegdkfklnkselkelltrelpswlgkrtdeaafqklms
nldsnrdnevdfqeycvflssiammsneffegfpdkqprk

  • Chain 'Q':
    No sequence available.