PDB entry 4cfk

View 4cfk on RCSB PDB site
Description: n-terminal bromodomain of human brd4 with ly294002
Class: cell cycle
Keywords: cell cycle, inhibitor, histone, epigenetic reader, antagonist
Deposited on 2013-11-18, released 2014-01-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-03-05, with a file datestamp of 2014-02-28.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: 0.23221
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: brd4 protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6NXE4 (0-126)
      • conflict (1)
    Domains in SCOPe 2.07: d4cfka_
  • Heterogens: GOL, LY2, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4cfkA (A:)
    smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
    ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
    nelptee