PDB entry 4cf6

View 4cf6 on RCSB PDB site
Description: Crystal structure of the complex of the P187S variant of human NAD(P) H:quinone oxidoreductase with Cibacron blue at 2.7 A resolution
Class: oxidoreductase
Keywords: flavoprotein, oxidoreductase, oxidoreductase-inhibitor complex, single amino acid exchange
Deposited on 2013-11-13, released 2014-08-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 2.69 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15559
      • engineered mutation (206)
    Domains in SCOPe 2.08: d4cf6a_
  • Chain 'B':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15559 (Start-293)
      • engineered mutation (206)
    Domains in SCOPe 2.08: d4cf6b_
  • Heterogens: FAD, CBD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cf6A (A:)
mgsshhhhhhssglvprgshmvgrralivlahsertsfnyamkeaaaaalkkkgwevves
dlyamnfnpiisrkditgklkdpanfqypaesvlaykeghlspdivaeqkkleaadlvif
qfplqwfgvpailkgwfervfigefaytyaamydkgpfrskkavlsittggsgsmyslqg
ihgdmnvilwpiqsgilhfcgfqvlesqltysightpadariqilegwkkrleniwdetp
lyfapsslfdlnfqagflmkkevqdeeknkkfglsvghhlgksiptdnqikark

    Sequence, based on observed residues (ATOM records): (download) 
    >4cf6A (A:)
rralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgklkdp
anfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwfervfig
efaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfcgfq
vlesqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmkkev
qdeeknkkfglsvghhlgksiptdnqikar

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4cf6B (B:)
mgsshhhhhhssglvprgshmvgrralivlahsertsfnyamkeaaaaalkkkgwevves
dlyamnfnpiisrkditgklkdpanfqypaesvlaykeghlspdivaeqkkleaadlvif
qfplqwfgvpailkgwfervfigefaytyaamydkgpfrskkavlsittggsgsmyslqg
ihgdmnvilwpiqsgilhfcgfqvlesqltysightpadariqilegwkkrleniwdetp
lyfapsslfdlnfqagflmkkevqdeeknkkfglsvghhlgksiptdnqikark

    Sequence, based on observed residues (ATOM records): (download) 
    >4cf6B (B:)
rralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgklkdp
anfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwfervfig
efaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfcgfq
vlesqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmkkev
qdeeknkkfglsvghhlgksiptdnqikark