PDB entry 4cew
View 4cew on RCSB PDB site
Description: Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor ALD
Class: virus
Keywords: virus, hand-foot-and-mouth disease, enterovirus uncoating, inhibitor
Deposited on
2013-11-12, released
2014-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-02-06, with a file datestamp of
2019-02-01.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.17
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: vp1
Species: ENTEROVIRUS A71 [TaxId:39054]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4cewa_ - Chain 'B':
Compound: vp2
Species: ENTEROVIRUS A71 [TaxId:39054]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4cewb_ - Chain 'C':
Compound: vp3
Species: ENTEROVIRUS A71 [TaxId:39054]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4cewc_ - Chain 'D':
Compound: vp4
Species: ENTEROVIRUS A71 [TaxId:39054]
Database cross-references and differences (RAF-indexed):
- Heterogens: 7J5, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4cewA (A:)
gdrvadviessigdsvsralthalpaptgqntqvsshrldtgkvpalqaaeigassnasd
esmietrcvlnshstaettldsffsraglvgeidlplegttnpngyanwdiditgyaqmr
rkvelftymrfdaeftfvactptgevvpqllqymfvppgapkpdsreslawqtatnpsvf
vklsdppaqvsvpfmspasayqwfydgyptfgehkqekdleygacpnnmmgtfsvrtvgt
skskyplvvriymrmkhvrawiprpmrnqnylfkanpnyagnsikptgasrtaittl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4cewB (B:)
spsaeacgysdrvaqltignstittqeaaniivgygewpsycsdsdatavdkptrpdvsv
nrfytldtklweksskgwywkfpdvltetgvfgqnaqfhylyrsgfcihvqcnaskfhqg
allvavlpeyvigtvaggtgtedthppykqtqpgadgfelqhpyvldagipisqltvcph
qwinlrtnncatiivpyinalpfdsalnhcnfgllvvpispldydqgatpvipititlap
mcsefaglrqavtq
Sequence, based on observed residues (ATOM records): (download)
>4cewB (B:)
sdrvaqltignstittqeaaniivgygewpsycsdsdatavdkptrpdvsvnrfytldtk
lweksskgwywkfpdvltetgvfgqnaqfhylyrsgfcihvqcnaskfhqgallvavlpe
yvigtvaggtgtedthppykqtqpgadgfelqhpyvldagipisqltvcphqwinlrtnn
catiivpyinalpfdsalnhcnfgllvvpispldydqgatpvipititlapmcsefaglr
qavtq
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>4cewC (C:)
gfptelkpgtnqflttddgvsapilpnfhptpcihipgevrnllelcqvetilevnnvpt
natslmerlrfpvsaqagkgelcavfradpgrngpwqstllgqlcgyytqwsgslevtfm
ftgsfmatgkmliaytppggplpkdratamlgthviwdfglqssvtlvipwisnthyrah
ardgvfdyyttglvsiwyqtnyvvpigapntayiialaaaqknftmklckdasdilqtgt
iq
- Chain 'D':
No sequence available.