PDB entry 4ceg

View 4ceg on RCSB PDB site
Description: Crystal structure of Aurora A 122-403 C290A, C393A bound to ADP
Class: transferase
Keywords: transferase, protein kinase, mitosis
Deposited on 2013-11-11, released 2015-01-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-06, with a file datestamp of 2019-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aurora kinase A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14965
      • engineered mutation (171)
    Domains in SCOPe 2.08: d4cega_
  • Heterogens: ADP, GOL, MG, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cegA (A:)
gameskkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehql
rreveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyit
elanalsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlagtldylpp
emiegrmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegard
lisrllkhnpsqrpmlrevlehpwitansskpsnaqnkesaskqs

    Sequence, based on observed residues (ATOM records): (download) 
    >4cegA (A:)
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlagtldylppemiegrmh
dekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkh
npsqrpmlrevlehpwitansskps