PDB entry 4cdx

View 4cdx on RCSB PDB site
Description: Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor GPP12
Class: virus
Keywords: virus, hand-foot-and-mouth disease, enterovirus uncoating, inhibitor
Deposited on 2013-11-07, released 2014-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-06, with a file datestamp of 2019-02-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: vp1
    Species: ENTEROVIRUS A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4cdxa_
  • Chain 'B':
    Compound: vp2
    Species: ENTEROVIRUS A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4cdxb_
  • Chain 'C':
    Compound: vp3
    Species: ENTEROVIRUS A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4cdxc_
  • Chain 'D':
    Compound: vp4
    Species: ENTEROVIRUS A71 [TaxId:39054]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: JF0, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4cdxA (A:)
gdrvadviessigdsvsralthalpaptgqntqvsshrldtgkvpalqaaeigassnasd
esmietrcvlnshstaettldsffsraglvgeidlplkgttnpngyanwdiditgyaqmr
rkvelftymrfdaeftfvactptgevvpqllqymfvppgapkpdsreslawqtatnpsvf
vklsdppaqvsvpfmspasayqwfydgyptfgehkqekdleygacpnnmmgtfsvrtvgt
skskyplvvriymrmkhvrawiprpmrnqnylfkanpnyagnsikptgasrtaittl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4cdxB (B:)
spsaeacgysdrvaqltignstittqeaaniivgygewpsycsdsdatavdkptrpdvsv
nrfytldtklweksskgwywkfpdvltetgvfgqnaqfhylyrsgfcihvqcnaskfhqg
allvavlpeyvigtvaggtgtedthppykqtqpgadgfelqhpyvldagipisqltvcph
qwinlrtnncatiivpyinalpfdsalnhcnfgllvvpispldydqgatpvipititlap
mcsefaglrqavtq

    Sequence, based on observed residues (ATOM records): (download) 
    >4cdxB (B:)
sdrvaqltignstittqeaaniivgygewpsycsdsdatavdkptrpdvsvnrfytldtk
lweksskgwywkfpdvltetgvfgqnaqfhylyrsgfcihvqcnaskfhqgallvavlpe
yvigtvaggtgtedthppykqtqpgadgfelqhpyvldagipisqltvcphqwinlrtnn
catiivpyinalpfdsalnhcnfgllvvpispldydqgatpvipititlapmcsefaglr
qavtq

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4cdxC (C:)
gfptelkpgtnqflttddgvsapilpnfhptpcihipgevrnllelcqvetilevnnvpt
natslmerlrfpvsaqagkgelcavfradpgrngpwqstllgqlcgyytqwsgslevtfm
ftgsfmatgkmliaytppggplpkdratamlgthviwdfglqssvtlvipwisnthyrah
ardgvfdyyttglvsiwyqtnyvvpigapntayiialaaaqknftmklckdasdilqtgt
iq

  • Chain 'D':
    No sequence available.